Forskolin is a phytochemical, characteristic of labdane diterpene and produced by Plectranthus barbatus which is commonly called the Indian Coleus plant. It is a very important biological tool used to stimulate cAMP and regulate cell physiological pathways. Apart from Forskolin, there are other chemical compounds present in the plant which have potential effects on human health. This is why, the plant is gaining spotlight in the field of medical science for preparations of different medications and health products.
What does Forskolin do inside your body?
Forskolin is actually the phytochemical that is extracted from the root of Indian Coleus plant and has shown beneficial effects in curing asthma, obesity and cardiac problems. From several clinical trials it has been found out that if Forskolin supplements are taken at 10 mg per day for two months to six months, it aids in the treatment of patients suffering from breathing disorders at a great extent. The root extract has been widely used as both oral and inhaled form for treating asthmatic patients. The major pathway by which Forskolin works is by raising the levels of cyclic adenosine mono phosphate (cAMP), which is involved in several important biochemical processes where there is an energy exchange taking place. Enhanced stimulation of cAMP levels leads to rapid rate of fat burning, as the overall metabolic rate of the body gets accelerated. Speedy metabolism of fat facilitates higher production of glycogen, which is stored in the form of glucose molecules in myocytes to provide energy to the overworking muscle tissues.
Forskolin has also proved promising results in improving cardiovascular activity by influencing the stimulation of adenylyl cyclase enzyme, involved in the conversion of ATP to cAMP with a release of inorganic pyrophosphate molecule. The plant extract causes relaxation of the constricted blood vessels and improves the rate of blood flow. Since Forskolin acts as anti-blood clotting agent or antithrombotic agent, the flow of blood in the auricles and ventricle of the cardiac walls becomes smooth that solves the issues associated with blood clots in cardiovascular system. Forskolin has also shown its positive effects on the immune system and cellular response, during cases of autoimmune diseases and diabetes. It even stimulates the central nervous system (CNS) in a beneficial way to enhance mental clarity and concentration.
How to regulate your doses?
Forskolin is a part of several clinical experiments where its effect on body weight and asthmatic problems are being hugely studied. Subsequent reports from different users show that the root extract has got positive influence in both the cases. Common dosage plan projects 50mg of Forskolin supplements to be taken 1-3 times daily. General dosage measurement of fluid forms of the extract ranges between 6-12 mL daily. Even less concentrated form of 250 mg taken once or thrice daily is also common, containing 1% forskolin.
The standardised safe level dosage plan recommended by experts for all users is 2-4 mL containing 10-20% forskolin, taken 2-3 times per day. To ensure safety level of the supplement, continue the dosage of 10 mg per day for two months and experience the amazing health benefits without facing serious adverse issues.